AN ADVANCEMENT IN CROSSLINKING
TECHNOLOGY FOR SOFT TISSUE REPAIR
XI-S+® PROCESSING
The proprietary Colorado Therapeutics tissue processing technology is the result of years of accumulated research and development into developing a superior biologic tissue for use in a multitude of soft tissue repair applications.
STRENGTH AND DURABILITY
Through Tissue Crosslinking
‣Highest burst strength/unit thickness among competitive products1,2
‣Tensile strength superior to competitive crosslinked products1
‣Maintains comparable strength at 6 months to tissues over 9 times as thick1
SUPPORTS ANGIOGENESIS
Undetectable Glutaraldehyde Residuals1
‣Proprietary process removes glutaraldehyde residuals below detectable limits (<0.97μg/mL)1
‣Tissue demonstrates angiogenesis and endothelialization1
‣Robust angiogenesis demonstrated after 21 days1
‣Healthy cell adhesion within 24 hours1
EASY TO USE
Ultra-thin and Translucent
‣No hydration required
‣Pliable like native tissue; easy to trim and contour
‣Suture and tack while visualizing critical organs and vessels
SAFETY AND BIOCOMPATIBILITY
Confidence by design
‣Meets all ISO 10993-1 biocompatibility requirements1
‣Lower mineralization than competitive crosslinked products at 6 months1
‣Proprietary processing assures viral inactivation1
‣Terminally sterilized with ethylene oxide
1 Colorado Therapeutics LLC. Data on file.
2 Corey Deeken et. al., Differentiation of Biologic Scaffold Materials Through Physicomechanical, Thermal, and Enzymatic Degradation Techniques. Annals of Surgery; March 2012
