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chemistry
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AN ADVANCEMENT IN CROSSLINKING

TECHNOLOGY FOR SOFT TISSUE REPAIR

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XI-S+® PROCESSING

The proprietary Colorado Therapeutics tissue processing technology is the result of years of accumulated research and development into developing a superior biologic tissue for use in a multitude of soft tissue repair applications.

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STRENGTH AND DURABILITY

Through Tissue Crosslinking

‣Highest burst strength/unit thickness among competitive products1,2
‣Tensile strength superior to competitive crosslinked products1
‣Maintains comparable strength at 6 months to tissues over 9 times as thick1

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SUPPORTS ANGIOGENESIS

Undetectable Gluteraldehyde Residuals1

‣Proprietary process removes gluteraldehyde residuals below detectable limits (<0.97μg/mL)1
‣Tissue demonstrates angiogenesis and endothelialization1
‣Robust angiogenesis demonstrated after 21 days1
‣Healthy cell adhesion within 24 hours1

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EASY TO USE

Ultra-thin and Translucent

‣No hydration required
‣Pliable like native tissue; easy to trim and contour
‣Suture and tack while visualizing critical organs and vessels

laproscopic
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SAFETY AND BIOCOMPATIBILITY

Confidence by design

‣Meets all ISO 10993-1 biocompatibility requirements1
‣Lower mineralization than competitive crosslinked products at 6 months1
‣Proprietary processing assures viral inactivation1
‣Terminally sterilized with ethylene oxide


1 Colorado Therapeutics LLC. Data on file.
2 Corey Deeken et. al., Differentiation of Biologic Scaffold Materials Through Physicomechanical, Thermal, and Enzymatic Degradation Techniques. Annals of Surgery; March 2012

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